Application
Western blot analysis of TBPIP expression in Hep G2 whole cell lysate.| Product Name | TBPIP Antibody (T-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of TBPIP of human origin by WB, IP and ELISA |
| Modification Notes | TBPIP (TBP-1-interacting protein), also known as PSMC3IP (PSMC3 interacting protein) or HOP2, is a 217 amino acid protein that localizes to the nucleus and is subject to phosphorylation by PKA, PKC or MAPK. Expressed at high levels in colon and testis, TBPIP functions to stimulate Dmc1-mediated strand exchange, thereby playing an important role in the pairing of homologous chromosomes during meiosis and during meiotic recombination. Human TBPIP shares 88% sequence identity with its mouse counterpart, suggesting a conserved role between species. TBPIP exists as multiple alternatively spliced isoforms and, when overexpressed, may be involved in the development of leiomyomas; benign soft tissue neoplasms that are found in smooth muscle. The gene encoding TBPIP maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TBPIP of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TBPIP of human origin by WB, IP and ELISA |
| Entrez Gene | 29893 |
|---|
Application
Western blot analysis of TBPIP expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
