| Product Name | Na+ CP type VIIα Antibody (C-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of Na+ CP type VIIα of mouse, rat and human origin by WB, IF and IHC(P) |
| Modification Notes | Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming å subunit, a noncovalently associated ∫1 subunit and a disulfide-linked ∫2 subunit. Na+ CP type VIIå (Sodium channel protein type 7 subunit alpha), also known as SCN6A, Sodium channel protein cardiac and skeletal muscle subunit alpha and putative voltage-gated sodium channel subunit alpha Nax, is a 1682 amino acid multi-pass membrane protein that belongs to the sodium channel family. Primarily expressed in uterus and heart, Na+ CP type VIIå may function in the regulation of salt intake behavior and central sensing of body-fluid sodium levels. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFIHC |
| WB:1:500~1:2000 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of Na+ CP type VII&alpha of mouse rat and human origin by WB IF and IHC(P) |
|---|---|
| Tissue Specificity | recommended for detection of Na+ CP type VIIα of mouse, rat and human origin by WB, IF and IHC(P) |
| Entrez Gene | 6332 |
|---|
| Application Notes | WB:1:500~1:2000 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
