Application
Western blot analysis of ACSBG1 expression in non-transfected: (A) and human ACSBG1 transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).Application
Western blot analysis of ACSBG1 expression in mouse brain tissue extract.| Product Name | ACSBG1 Antibody (M-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of ACSBG1 of mouse, rat and human origin by WB, IP, IF and IHC(P) |
| Modification Notes | ACSBG1 (acyl-CoA synthetase bubblegum family member 1), also known as Lipodisin, BG1, BGM, LPD or GR-LACS, is a 724 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and belongs to the ATP-dependent AMP-binding enzyme family. Expressed primarily in brain and at lower levels in adrenal gland and testis, ACSBG1 functions to mediate the activation of long-chain and very long-chain fatty acids, thereby playing an important role in the synthesis and degradation of cellular lipids. Defects in the gene encoding ACSBG1 may be associated with X-linked adrenoleukodystrophy (X-ALD), a neurodegenerative disorder that affects the adrenal glands and the white matter of the brain and is characterized by urinary disturbances, sensory loss and cognitive defects. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHC |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ACSBG1 of mouse rat and human origin by WB IP IF and IHC(P) |
|---|---|
| Tissue Specificity | recommended for detection of ACSBG1 of mouse, rat and human origin by WB, IP, IF and IHC(P) |
| Entrez Gene | 23205 |
|---|
Application
Western blot analysis of ACSBG1 expression in non-transfected: (A) and human ACSBG1 transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).
Application
Western blot analysis of ACSBG1 expression in mouse brain tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
