| Product Name | NPT1 Antibody (M-75) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-75 mapping at the N-terminus of NPT1 of mouse origin |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1å and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIPWB |
| WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-75 mapping at the N-terminus of NPT1 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-75 mapping at the N-terminus of NPT1 of mouse origin |
| Entrez Gene | 20504 |
|---|
| Application Notes | WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
