Application
Western blot analysis of Autotaxin expression in non-transfected: (A) and human Autotaxin transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Autotaxin expression in non-transfected: (A) and mouse Autotaxin transfected: (B) 293T whole cell lysates.| Product Name | Autotaxin Antibody (H-180) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 541-720 mapping within a C-terminal extracellular domain of Autotaxin of human origin |
| Modification Notes | Autotaxin (ATX), also designated ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2), is a membrane-bound glycoprotein that cleaves diester bonds for a broad range of substrates. Originally isolated from the human melanoma cell line (A2058), Autotaxin is predominantly expressed in brain, placenta, ovary and small intestine. Autotaxin has significant homology to the cell membrane differentiation antigen PC-1, and is a stimulator of tumor cell motility. It also functions as a catalyst by hydrollytically removing 5’-nucleotides from the 3’-hydroxy termini of 3'-hydroxy-terminated oligonucleotides. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Autotaxin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 541-720 mapping within a C-terminal extracellular domain of Autotaxin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 541-720 mapping within a C-terminal extracellular domain of Autotaxin of human origin |
| Entrez Gene | 5168 |
|---|
Application
Western blot analysis of Autotaxin expression in non-transfected: (A) and human Autotaxin transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Autotaxin expression in non-transfected: (A) and mouse Autotaxin transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Autotaxin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
