| Product Name | MYL Antibody (H-75) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 121-195 mapping at the C-terminus of MYL3 of human origin |
| Modification Notes | Myosin, the major component of thick muscle filaments, is a long asymmetric molecule containing a globular head and a long tail. Activation of smooth and cardiac/ventricular muscle primarily involves pathways which increase calcium and Myosin phosphorylation, resulting in contraction. In vertebrate striated muscle, Myosin is composed of two heavy chains and four light chains. There are two distinct types of light chains: the phosphorylatable, regulatory or MLC2 type, and the non-phosphorylatable, alkali or MLC1 and MLC3 types. The role of Myosin alkali light chains in vertebrate skeletal muscle is poorly understood, although alkali light chains in smooth muscle may be involved with the active site of Myosin. Several Myosin alkali light chains have been identified and include MYL1, MYL3, MYL4 and MYL6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MYL1, MYL3, MYL4 and MYL6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 121-195 mapping at the C-terminus of MYL3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 121-195 mapping at the C-terminus of MYL3 of human origin |
| Entrez Gene | 4634 |
|---|
| Application Notes | recommended for detection of MYL1, MYL3, MYL4 and MYL6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
