| Product Name | SmarcAL1 Antibody (H-124) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 831-954 mapping at the C-terminus of SmarcAL1 of human origin |
| Modification Notes | SmarcAL1 (SWI/SNF-related matrix-associated Actin-dependent regulator of chromatin subfamily A-like protein 1), also known as HARP (HepA-related protein) or HHARP, is a 954 amino acid member of the SWI/SNF family of helicase and ATPase proteins. Localized to the nucleus, SmarcAL1 is a ubiquitously expressed protein that functions in ATP-dependent nucleosome-remodeling activities. SmarcAL1 contains one conserved C-terminal SNF2 domain, one helicase ATP-binding domain and two HARP domains. Defects in the gene encoding SmarcAL1 are the cause of Schimke immuno-osseous dysplasia (SIOD), an autosomal recessive disorder characterized by renal dysfunction, spondyloepiphyseal dysplasia and T cell immunodeficiency. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SmarcAL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 831-954 mapping at the C-terminus of SmarcAL1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 831-954 mapping at the C-terminus of SmarcAL1 of human origin |
| Entrez Gene | 50485 |
|---|
| Application Notes | recommended for detection of SmarcAL1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
