Application
Western blot analysis of TMEM14C expression in non-transfected 293T: (A), human TMEM14C transfected 293T: (B), ES-D3 (C) and SK-MEL-28 (D) whole cell lysates.Application
Western blot analysis of TMEM14C expression in non-transfected 293T: (A), mouse TMEM14C transfected 293T: (B), ES-D3 (C) and SK-MEL-28 (D) whole cell lysates.| Product Name | TMEM14C Antibody (Y-9) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of TMEM14C of human origin |
| Modification Notes | TMEM14C (transmembrane protein 14C) is a 112 amino acid protein encoded by a gene mapping to human chromosome 6. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMEM14C of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TMEM14 family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TMEM14C of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TMEM14C of human origin |
| Entrez Gene | 51522 |
|---|
Application
Western blot analysis of TMEM14C expression in non-transfected 293T: (A), human TMEM14C transfected 293T: (B), ES-D3 (C) and SK-MEL-28 (D) whole cell lysates.
Application
Western blot analysis of TMEM14C expression in non-transfected 293T: (A), mouse TMEM14C transfected 293T: (B), ES-D3 (C) and SK-MEL-28 (D) whole cell lysates.| Application Notes | recommended for detection of TMEM14C of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TMEM14 family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
