| Product Name | TACI Antibody (FL-249) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-249 representing full length TACI of mouse origin |
| Modification Notes | The NFAT (nuclear factor of activated T cells) family of transcription factors regulates cytokine expression in T cells through cis-acting elements located in the promoters of the cytokine genes (1–5). The NFAT family consists of the cytoplasmic NFAT (NFATc), transcription factors NFATc1, NFATc2, NFATc3 and NFATc4, and nuclear NFAT (NFATn) (6). Each of these transcription factors plays a role in T cell activation (1). CAML (calcium-signal modulating cyclophilin ligand) has been identified as an activator of NFAT and NF-IL2A when overexpressed in Jurkat cells. CAML has also been shown to activate calcineurin by causing calcium influx (7). TACI (transmembrane activator and CAML-interactor), a member of the TNF receptor superfamily, was identified based on its capacity to bind to CAML and has been shown to induce activation of NFAT in the presence of CAML (8). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TACI of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-249 representing full length TACI of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-249 representing full length TACI of mouse origin |
| Entrez Gene | 57916 |
|---|
| Application Notes | recommended for detection of TACI of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
