Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing cytoskeletal localization.Application
Western blot analysis of ANKRD29 expression in mouse lung (A) and mouse brain (B) tissue extracts.| Product Name | ANKRD29 Antibody (K-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ANKRD29 of human origin |
| Modification Notes | Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD29 (ankyrin repeat domain-containing protein 29) is a 301 amino acid protein that contains 8 ankyrin repeats and exists as three alternatively spliced isoforms. The gene encoding human ANKRD29 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ANKRD29 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ANKRD29 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ANKRD29 of human origin |
| Entrez Gene | 147463 |
|---|
Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing cytoskeletal localization.
Application
Western blot analysis of ANKRD29 expression in mouse lung (A) and mouse brain (B) tissue extracts.| Application Notes | recommended for detection of ANKRD29 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
