epitope mapping within an internal region of WDR54 of human origin
Conjugation
Agarose
Modification
Acetylated
Modification Notes
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR54 (WD repeat-containing protein 54) is a 334 amino acid protein that contains four WD repeats and is encoded by a gene that maps to human chromosome 2p13.1. Chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alström syndrome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIFIPWB
WB:1:100~1:400 IP:1:20~1:100 IF:1:20~1:100
Species Reactivity
HumanMouseRat
Predicted Reactivity
canine, bovine and porcine
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of WDR54 of human origin
Tissue Specificity
epitope mapping within an internal region of WDR54 of human origin