Application
Western blot analysis of TBC1D2B expression in non-transfected: (A) and human TBC1D2B transfected: (B) 293T whole cell lysates.| Product Name | TBC1D2B Antibody (Y-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of TBC1D2B of human origin |
| Modification Notes | GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. TBC1D2B (TBC1 domain family, member 2B) is a 963 amino acid protein that is thought to play a role in GTPase activation. Containing one PH domain and a Rab-GAP TBC domain, TBC1D2B exists as three alternatively spliced isoforms. The gene encoding TBC1D2B maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TBC1D2B of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TBC1D family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TBC1D2B of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TBC1D2B of human origin |
| Entrez Gene | 23102 |
|---|
Application
Western blot analysis of TBC1D2B expression in non-transfected: (A) and human TBC1D2B transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of TBC1D2B of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TBC1D family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
