| Product Name | ARMS Antibody (R-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1463-1762 mapping at the C-terminus of ARMS of rat origin |
| Modification Notes | Ankyrin repeat-rich membrane-spanning protein (ARMS), also designated kinase D-interacting substance 220 or Kidins220, is a highly conserved, 1715 amino acid protein containing multiple domains, including four putative transmembrane domains and several ankyrin repeats. ARMS is expressed in regions rich in neurotrophin (Trk) and ephrin (Eph) receptors, such as the brain and neuroendocrine cells (where it concentrates at the tip of neurites) and in plastic areas of the adult brain. It is also detected in peripheral blood immature dendritic cells and PC12 cells. ARMS functions as a substrate for protein kinase D and is a downstream target for both Trk and Eph receptors. It is a highly conserved protein, which suggests it has an evolutionary conserved role. The gene encoding for the protein maps to chromosome 2p24. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ARMS of rat origin and Kidins220 of human and mouse origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1463-1762 mapping at the C-terminus of ARMS of rat origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1463-1762 mapping at the C-terminus of ARMS of rat origin |
| Entrez Gene | 57498 |
|---|
| Application Notes | recommended for detection of ARMS of rat origin and Kidins220 of human and mouse origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
