Application
Western blot analysis of SULT1A1 expression in non-transfected: (A) and human SULT1A1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of SULT1 expression in non-transfected: (A) and human SULT1 transfected: (B) 293 whole cell lysates.Application
Western blot analysis of SULT1 expression in Hep G2 whole cell lysate.| Product Name | SULT1 Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 51-105 mapping within an internal region of Sulfotransferase 1A1 of human origin |
| Modification Notes | The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily show selectivity to certain substrate compounds. SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. High SULT1 activity is associated with an increased protection against many of the carcinogens that lead to colorectal cancer. Activity of the SULT1A1 allele is higher in the elderly, possibly because of protection conferred by SULT1 against cell and tissue damage brought on by aging. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Sulfotransferase 1A1, 1A2 and 1A3 of human origin and Sulfotransferase 1A1 of rat origin by WB, IP, IF and ELISA partially cross-reactive other SULT family members of human origin also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 51-105 mapping within an internal region of Sulfotransferase 1A1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 51-105 mapping within an internal region of Sulfotransferase 1A1 of human origin |
| Entrez Gene | 6799 |
|---|
Application
Western blot analysis of SULT1A1 expression in non-transfected: (A) and human SULT1A1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of SULT1 expression in non-transfected: (A) and human SULT1 transfected: (B) 293 whole cell lysates.
Application
Western blot analysis of SULT1 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of Sulfotransferase 1A1, 1A2 and 1A3 of human origin and Sulfotransferase 1A1 of rat origin by WB, IP, IF and ELISA partially cross-reactive other SULT family members of human origin also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
