| Product Name | TLR11 Antibody (M-72) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 658-729 mapping within an internal region of TLR11 of mouse origin |
| Modification Notes | Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated toll-like receptors (TLR). Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo and also participate in the host immunity. The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR11 is a single-pass type I membrane protein. It is involved the innate immune response to microbial agents. It acts through TRAF6 and MyD88, causing NF˚B activation, cytokine secretion and inflammatory response. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TLR11 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 658-729 mapping within an internal region of TLR11 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 658-729 mapping within an internal region of TLR11 of mouse origin |
| Entrez Gene | 239081 |
|---|
| Application Notes | recommended for detection of TLR11 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
