| Product Name | Tastin Antibody (M-230) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 3-232 mapping near the N-terminus of Tastin of mouse origin |
| Modification Notes | Tastin (trophinin associated protein), also known as TROAP, is essential for centrosome integrity and proper bipolar organization of spindle assembly during mitosis. It is expressed at high levels in bone marrow, testis, and thymus, localizing to the cytoplasm and associating with microtubules, the mitotic spindle and centrosomes. Tastin expression peaks in the cell during the G2/M phase and declines after the cell divides. Cells overexpresssing Tastin form monopolar spindles, while cells depleted of Tastin form multipolar spindles. Tastin binds directly to the Dynein light chain (Dynein LC or Tctex-1) and © Tubulin, further supporting its role in spindle assembly and cell proliferation. In addition, Tastin can interact with and form a complex with Bystin and Trophinin, facilitating cell adhesion and, in particular, embryo implantation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Tastin of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 3-232 mapping near the N-terminus of Tastin of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 3-232 mapping near the N-terminus of Tastin of mouse origin |
| Entrez Gene | 78733 |
|---|
| Application Notes | recommended for detection of Tastin of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
