| Product Name | Pannexin-3 Antibody (H-176) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 68-243 mapping within an internal region of Pannexin-3 of human origin |
| Modification Notes | Gap junctions are formed by a hexameric group of proteins called connexins for the transport of low molecular weight proteins from cell to cell. Connexins, which are present in all metazoan organisms, serve diverse functions ranging from control of cell growth and differentiation to electric conduction in excitable tissues. Several mammalian cells with malignant phenotypes exhibit decreased connexin expression and gap junction communication. The pannexin gene family encodes a second class of putative gap junction proteins. Pannexins are highly conserved in invertebrates and mammals, indicating the importance of their gap junctional coupling function. Mammalian Pannexin-3 and Pannexin-1 are closely related, while Pannexin-2 is more distantly related. Pannexin-3 is a multi-pass membrane protein that is not associated with channel activity or modulatory function. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Pannexin-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 68-243 mapping within an internal region of Pannexin-3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 68-243 mapping within an internal region of Pannexin-3 of human origin |
| Entrez Gene | 116337 |
|---|
| Application Notes | recommended for detection of Pannexin-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
