| Product Name | SCRN3 Antibody (E-11) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of SCRN3 of human origin |
| Modification Notes | SCRN3 (secernin 3), also known as SES3, is a 424 amino acid cytosolic protein that belongs to the peptidase C69 family and secernin subfamily. SCRN3 participates in exocytosis from peritoneal mast cells and is encoded by a gene that maps to human chromosome 2q31.1. As the second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome is due to mutations in the ALMS1 gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of SCRN3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with SCRN1 or SCRN2: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of SCRN3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of SCRN3 of human origin |
| Entrez Gene | 79634 |
|---|
| Application Notes | recommended for detection of SCRN3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with SCRN1 or SCRN2: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
