Application
Western blot analysis of BTBD2 expression in human PBL whole cell lysate.| Product Name | BTBD2 Antibody (H-43) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-43 mapping at the N-terminus of BTBD2 of human origin |
| Modification Notes | BTBD2 (BTB/POZ domain-containing protein 2) is a 525 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD2 may play a role in transcription regulation. BTBD2 is expressed as two isoforms produced by alternative splicing events and has been found to interact with Topo I and Trim5∂. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BTBD2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-43 mapping at the N-terminus of BTBD2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-43 mapping at the N-terminus of BTBD2 of human origin |
Application
Western blot analysis of BTBD2 expression in human PBL whole cell lysate.| Application Notes | recommended for detection of BTBD2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
