epitope corresponding to amino acids 380-579 of RelB of human origin
Modification Notes
The NF˚B transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NF˚B subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NF˚B homodimers. However, Rel B/p50 heterodimers, in contrast to NF˚B heterodimers, transactivates transcription of promotors containing ˚B binding sites.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISAGSChIP
recommended for detection of RelB of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 380-579 of RelB of human origin
Tissue Specificity
epitope corresponding to amino acids 380-579 of RelB of human origin
Western blot analysis of RelB expression in KNRK whole cell lysate.
Application
Western blot analysis of RelB expression in non-transfected: (A) and human RelB transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of RelB of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.