| Product Name | Vasorin Antibody (H-167) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 434-600 mapping near the C-terminus of Vasorin of human origin |
| Modification Notes | Vasorin (SLITL2, slit-like 2 (Drosophila)) is a secreted type I membrane protein that participates in vertebrate axis patterning, axon guidance, and vessel development. Vasorin contains tandem leucine-rich repeats, an EGF-like motif, and a fibronectin type III-like motif in the extracellular domain. Vasorin transcripts appear in aorta, with moderate expression in kidney and placenta. Vasorin directly binds to transforming growth factor (TGF)-∫ and attenuates TGF-∫ signaling in vitro. Down-regulation of vasorin expression contributes to neointimal formation after vascular injury and this mechanism modulates response to pathological stimuli in vessel walls. Subsequently, vasorin is a potential therapeutic target for vascular fibroproliferative disorders. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Vasorin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 434-600 mapping near the C-terminus of Vasorin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 434-600 mapping near the C-terminus of Vasorin of human origin |
| Entrez Gene | 114990 |
|---|
| Application Notes | recommended for detection of Vasorin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
