Application
Western blot analysis of RNF126 expression in NIH/3T3 (A), Jurkat (B), RAW 264.7 (C), PC-12 (D) and U-251 MG (E) whole cell lysates.| Product Name | RNF126 Antibody (H-106) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 41-146 mapping within an internal region of RNF126 of human origin |
| Modification Notes | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in protein-protein interactions and protein-DNA interactions. RNF126 (RING finger protein 126) contains one RING-type zinc finger domain and is known to interact with TRAF6 (a ubiquitin ligase) and BAT3 (an apoptotic regulator). RNF126 shares 46% overall amino acid identity with ZNF364 (an E3 ligase that is closely linked to human breast cancer) and 75% amino acid identity within the RING domain. This suggests that RNF126 may have a similar function to that of ZNF364. Due to alternative splicing events, two isoforms exist for RNF126. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RNF126 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 41-146 mapping within an internal region of RNF126 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 41-146 mapping within an internal region of RNF126 of human origin |
| Entrez Gene | 55658 |
|---|
Application
Western blot analysis of RNF126 expression in NIH/3T3 (A), Jurkat (B), RAW 264.7 (C), PC-12 (D) and U-251 MG (E) whole cell lysates.| Application Notes | recommended for detection of RNF126 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
