| Product Name | DSEL Antibody (L-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of DSEL of human origin |
| Modification Notes | DSEL, also known as NCAG1, is a 1,212 amino acid multi-pass membrane protein expressed in various regions of the brain and multiple peripheral tissues. Belonging to the dermatan-sulfate isomerase family, DSEL contains a chondroitin sulfate sulfotransferase domain, which suggests that DSEL may be involved in dermatan sulfate biosynthesis. Dermatan sulfate is believed be involved in iduronic acid-dependent interactions with growth factors, selectins, cytokines and coagulation inhibitors. The gene encoding DSEL is located on human chromosome 18 and has been linked to bipolar disease. Human chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of DSEL of mouse and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of DSEL of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of DSEL of human origin |
| Entrez Gene | 92126 |
|---|
| Application Notes | recommended for detection of DSEL of mouse and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
