epitope mapping within an internal region of ABHD10 of human origin
Modification Notes
The å/∫ hydrolase superfamily includes diverse members that are involved in important biochemical processes and are related to various diseases. They have unrelated sequences, various substrates and different kinds of catalytic activities, yet they share the same canonical å/∫ hydrolase fold, which consists of an eight-stranded parallel å/∫ structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer’s disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 relatively uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD10 is a 306 amino acid protein that localizes to mitochondria.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ABHD10 of human origin by WB, IP, IF and ELISA non cross-reactive with other ABHD family members:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of ABHD10 of human origin
Tissue Specificity
epitope mapping within an internal region of ABHD10 of human origin