Application
Western blot analysis of cadherin-19 expression in TE671 (A), MIA PaCa-2 (B) and IMR-32 (C) whole cell lysates.| Product Name | cadherin-19 Antibody (S-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within a cytoplasmic domain of cadherin-19 of human origin |
| Modification Notes | The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-19, also known as CDH19, CDH7 or CDH7L2, is a 772 amino acid single-pass type I membrane protein that contains five cadherin domains. Expressed in a variety of tissues, cadherin-19 functions as a Ca2+-dependent cell-cell adhesion glycoprotein that is thought to be involved in the sorting of heterogeneous cell types. The gene encoding cadherin-19 maps to a cadherin cluster on human chromosome 18, a chromosome which houses over 300 protein-coding genes and contains nearly 76 million bases. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of cadherin-19 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other cadherin family members also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a cytoplasmic domain of cadherin-19 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a cytoplasmic domain of cadherin-19 of human origin |
| Entrez Gene | 28513 |
|---|
Application
Western blot analysis of cadherin-19 expression in TE671 (A), MIA PaCa-2 (B) and IMR-32 (C) whole cell lysates.| Application Notes | recommended for detection of cadherin-19 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other cadherin family members also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
