epitope corresponding to amino acids 402-609 mapping within an internal region of Slk19p of Saccharomyces cerevisiae origin
Modification Notes
Slk19p (synthetic lethal Kar3p gene) is an outer kinetichore protein that moves to the spindle midzone in anaphase. Slk19p is essential for proper chromosome segregation during meiosis I. Saccharomyces cerevisiae strains with a deletion of the SLK19 gene exhibit abnormally short mitotic spindles, increased numbers of astral microtubules, and require the presence of the kinesin motor Kar3p for viability. When cells are deprived of both Slk19p and Kar3p, rapid spindle breakdown and mitotic arrest occurs. Slk19p and Kar3p play overlapping roles in stabilizing spindle structure while acting from opposite ends of the microtubules.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Slk19p of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 402-609 mapping within an internal region of Slk19p of Saccharomyces cerevisiae origin
Tissue Specificity
epitope corresponding to amino acids 402-609 mapping within an internal region of Slk19p of Saccharomyces cerevisiae origin
Application Notes
recommended for detection of Slk19p of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.