Application
Western blot analysis of IRF-5 expression in non-transfected: (A) and mouse IRF-5 transfected: (B) 293 whole cell lysates.| Product Name | IRF-5 Antibody (H-56) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 443-498 mapping at the C-terminus of IRF-5 of human origin |
| Modification Notes | Interferon regulatory factor 5 (IRF-5), belongs to the IRF family of DNA-binding factors, which includes IRF-1, IRF-2, IRF-3, IRF-4, IRF-6, IRF-7, ISGF-3© p48 and IFN consensus sequence-binding protein (ICSBP). The IRF family regulate both interferon and interferon-inducible genes. IRF-5, like IRF-3 and IRF-7, is a direct transducer of virus-mediated signaling and plays a role in the expression of multiple cytokines/chemokines. Although IRF-5 is a direct target of p53, its cell cycle regulatory and proapoptotic effects are p53 independent. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IRF-5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 443-498 mapping at the C-terminus of IRF-5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 443-498 mapping at the C-terminus of IRF-5 of human origin |
| Entrez Gene | 3663 |
|---|
Application
Western blot analysis of IRF-5 expression in non-transfected: (A) and mouse IRF-5 transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of IRF-5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
