| Product Name | RhD/CE Antibody (H-137) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 281-417 mapping at the C-terminus of Rhesus blood group CE antigen of human origin |
| Modification Notes | The Rhesus (Rh) blood group system represents one of the most complex and important systems in humans. Two highly homologous genes, RhD and RhCE (collectively referred to as Rh30 or RhCED), encode the antigens of the Rh blood group system. These tightly linked genes map to human chromosomal position 1p36.11. The RhD gene, which is commonly deleted from a large segment of the population, encodes the most potent blood group immunogen, the D antigen. Rh incompatibility between maternal and fetal blood types results in hemolytic disease of the newborn (HDN), which often results in fetal death. The RhCE gene exists in four allelic forms, and each allele determines the expression of two antigens in Ce, ce, cE, or CE combinations. The RhCED antigens exist as integral membrane proteins which contain 12-transmembrane helices and maintain erythrocyte membrane integrity. The presentation of the Rh antigenic activity requires the formation of a complex between the RhCED antigens and RhAG (Rh50). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RhCE and RhD of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 281-417 mapping at the C-terminus of Rhesus blood group CE antigen of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 281-417 mapping at the C-terminus of Rhesus blood group CE antigen of human origin |
| Entrez Gene | 6006 |
|---|
| Application Notes | recommended for detection of RhCE and RhD of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
