Application
Immunoperox-idase staining of formalin fixed, paraffin-embedded human epididymis tissue showing cytoplasmic staining of glandular cells.Application
Western blot analysis of L-type Ca++ CP α1D expression in non-transfected: (A) and mouse L-type Ca++ CP α1D transfected: (B) 293T whole cell lysates.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human hippocampus tissue showing nuclear membrane staining of non-neuronal cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of L-type Ca++ CP α1D expression in L6 whole cell lysate.| Product Name | L-type Ca++ CP α1D Antibody (H-240) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1661-1900 of L-type Ca++ CP α1D of human origin |
| Modification Notes | Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an å-1 subunit, an intracellular ∫-subunit, a disulfide linked å-2/∂ subunit and a transmembrane ©-subunit. Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. L-type Ca2+ currents initiate muscle contraction, endocrine secretion, and gene transcription, and can be regulated through second-messenger activated protein phosphorylation pathways. L-type calcium channels may form macromolecular signaling complexes with G protein-coupled receptors, thereby enhancing the selectivity of regulating specific targets. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of L-type Ca++ CP α1D of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1661-1900 of L-type Ca++ CP &alpha 1D of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1661-1900 of L-type Ca++ CP α1D of human origin |
| Entrez Gene | 776 |
|---|
Application
Immunoperox-idase staining of formalin fixed, paraffin-embedded human epididymis tissue showing cytoplasmic staining of glandular cells.
Application
Western blot analysis of L-type Ca++ CP α1D expression in non-transfected: (A) and mouse L-type Ca++ CP α1D transfected: (B) 293T whole cell lysates.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human hippocampus tissue showing nuclear membrane staining of non-neuronal cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of L-type Ca++ CP α1D expression in L6 whole cell lysate.| Application Notes | recommended for detection of L-type Ca++ CP α1D of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
