recommended for detection of Mitsugumin23 of human origin by WB, IP and ELISA
Modification Notes
With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Defects in chromosome 11 have been linked to many diseases, including Wilms' tumors, WAGR syndrome, and Denys-Drash syndrome, Sickle cell anemia and ∫ thalassemia. On chromosome 11q12.2 is a gene encoding Mitsugumin23. Mitsugumin23 (Mg23), also known as transmembrane protein 109 (TMEM109), is a 243 amino acid multi-pass transmembrane protein localized to the membrane of the nucleus, endoplasmic reticulum and sarcoplasmic reticulum. It is comprised of two primary domains: a 33 amino acid signal peptide and a 109 amino acid chain consisting of four transmembrane domains.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of Mitsugumin23 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of Mitsugumin23 of human origin by WB, IP and ELISA