Application
Western blot analysis of copine 3 expression in non-transfected: (A) and human copine 3 transfected: (B) 293T whole cell lysates.| Product Name | copine 3 Antibody (F-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of copine 3 of human origin |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | Copine 3, also known as CPNE3, CPN3 or COPN3, is a member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Copine 3 is ubiquitously expressed and contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 3 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Differing from other members of the copine family, copine 3 may possess some intrinsic kinase activity. Copine 3 exists as a monomer in the cytosol and undergoes a conformational change upon binding to calcium. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCIPWB |
| recommended for detection of copine 3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other copine family members also reactive with additional species, including canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of copine 3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of copine 3 of human origin |
| Entrez Gene | 8895 |
|---|
Application
Western blot analysis of copine 3 expression in non-transfected: (A) and human copine 3 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of copine 3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other copine family members also reactive with additional species, including canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
