Application
Western blot analysis of THAP7 expression in K-562 whole cell lysate.Application
Western blot analysis of THAP7 expression in non-transfected: (A) and mouse THAP7 transfected: (B) 293T whole cell lysates.| Product Name | THAP7 Antibody (Q-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of THAP7 of human origin |
| Modification Notes | THAP7 (THAP domain-containing protein 7) is a 309 amino acid protein belonging to the Thanatos-associated protein family. Ubiquitously expressed, with highest expression in testis, THAP7 contains one THAP domain, an approximately 90 amino acid residue domain which includes a C2CH signature, an AVPTIF box and several other conserved amino acids. In the nucleus, THAP7 associates with chromatin and binds preferentially to hypoacylated (un-, mono- and diacetylated) histones H3 and H4 through the C-terminal tail. In addition, THAP7 represses transcription by recruiting HDAC3 and N-CoR to promoters to deacetylate histone H3. The gene encoding human THAP7 is localized to chromosome 22q11.2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of THAP7 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with THAP1 also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of THAP7 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of THAP7 of human origin |
| Entrez Gene | 80764 |
|---|
Application
Western blot analysis of THAP7 expression in K-562 whole cell lysate.
Application
Western blot analysis of THAP7 expression in non-transfected: (A) and mouse THAP7 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of THAP7 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with THAP1 also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
