Application
Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.Application
Western blot analysis of SLC35E4 expression in HeLa whole cell lysate.| Product Name | SLC35E4 Antibody (S-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of SLC35E4 of human origin |
| Modification Notes | SLC35E4 (solute carrier family 35, member E4) is a 350 amino acid multi-pass membrane protein and putative transporter that contains one DUF6 domain. A member of the TPT transporter family and SLC35E subfamily, SLC35E4 is exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 22q12.2. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SLC35E4 of human origin by WB, IP, IF and ELISA non cross-reactive with other SLC35 family members also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of SLC35E4 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of SLC35E4 of human origin |
| Entrez Gene | 339665 |
|---|
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
Application
Western blot analysis of SLC35E4 expression in HeLa whole cell lysate.| Application Notes | recommended for detection of SLC35E4 of human origin by WB, IP, IF and ELISA non cross-reactive with other SLC35 family members also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
