Application
Western blot analysis of JRK expression in non-transfected: (A) and mouse JRK transfected: (B) 293T whole cell lysates.| Product Name | JRK Antibody (D-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of JRK of human origin |
| Modification Notes | JRK (jerky protein homolog) is also known as JH8 and is a 520 amino acid ortholog of the mouse Jerky protein. JRK is thought to translocate from the nucleolus to many nuclear foci during the S phase and G2 phase of the cell cycle. During mitosis, JRK is localized primarily to the cytoplasm, but may also be present as alternatively spliced isoforms that may be found in several other locations within the cell. The gene encoding JRK maps to human chromosome 8q24.3 and shares a locus with genes that are involved in the pathogenesis of Childhood Absence Epilepsy (CAE), suggesting that JRK may be associated with the development of CAE. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of JRK of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of JRK of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of JRK of human origin |
| Entrez Gene | 8629 |
|---|
Application
Western blot analysis of JRK expression in non-transfected: (A) and mouse JRK transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of JRK of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
