Application
Western blot analysis of CD160 expression in CTLL-2 (A) and rat PBL (B) whole cell lysates and mouse small intestines tissue extract (C).Application
Western blot analysis of CD160 expression in CTLL-2 whole cell lysate.Application
Western blot analysis of CD160 expression in mouse spleen tissue extract.Application
Western blot analysis of CD160 expression in Jurkat whole cell lysate.Application
Western blot analysis of CD160 expression in non-transfected: (A) and human CD160 transfected: (B) 293T whole cell lysates.| Product Name | CD160 Antibody (M-134) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 27-160 mapping within an internal region of CD160 of mouse origin |
| Modification Notes | CD160, also known as NK1, BY55 or NK28, is a 181 amino acid lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain. Expressed in small intestine, spleen and functional NK (natural killer) and T cytotoxic lymphocytes, CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells. Additionally, CD160 interacts with HVEM (herpesvirus entry mediator) and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation. Multiple isoforms of CD160 exist due to alternative splicing events. The gene encoding CD160 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CD160 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 27-160 mapping within an internal region of CD160 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 27-160 mapping within an internal region of CD160 of mouse origin |
| Entrez Gene | 54215 |
|---|
Application
Western blot analysis of CD160 expression in CTLL-2 (A) and rat PBL (B) whole cell lysates and mouse small intestines tissue extract (C).
Application
Western blot analysis of CD160 expression in CTLL-2 whole cell lysate.
Application
Western blot analysis of CD160 expression in mouse spleen tissue extract.
Application
Western blot analysis of CD160 expression in Jurkat whole cell lysate.
Application
Western blot analysis of CD160 expression in non-transfected: (A) and human CD160 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of CD160 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
