epitope mapping within an internal region of RWDD2B of human origin
Modification Notes
RWDD2B (RWD domain containing protein 2B), also known as C21orf6, is a 319 amino acid protein that is ubiquitously expressed. RWDD2B contains one RWD domain, a conserved region of about 110 amino acid residues. RWD domains are found in many RING finger proteins, DEAD-like helicases and WD repeat containing proteins. It is believed that RWD domains may be involved in protein interaction. The gene that encodes RWDD2B maps to chromosome 21, which makes up about 1.5% of the human genome. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of RWDD2B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of RWDD2B of human origin
Tissue Specificity
epitope mapping within an internal region of RWDD2B of human origin
Western blot analysis of RWDD2B expression in NIH/3T3 whole cell lysate.
Application Notes
recommended for detection of RWDD2B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.