| Product Name | Neurofascin Antibody (H-105) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1106-1210 mapping within an extracellular domain of Neurofascin of human origin |
| Modification Notes | Members of the L1 subgroup of the immunoglobulin (Ig) superfamily promote axon outgrowth by interactions with a neuronal NgCAM-related cell adhesion molecule. Neurofascin is a cell adhesion, ankyrin-binding, single-pass membrane protein that plays a role in neurite extension in embryonic development. It also is involved in synaptogenesis, myelination and neuron-glial cell interaction. Neurofascin may be a component of a Neurofascin/NRCAM/Ankyrin G complex and can dimerize in solution. The Neurofascin protein interacts with GLDN/gliomedin and associates with the sodium channel ∫-3 (SCN3B) and ∫-1 (SCNB1) subunits. It contains five Fibronectin type III domains and six Ig-like C2-type (immunoglobulin-like) domains. There are 13 known isoforms of the Neurofascin protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Neurofascin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1106-1210 mapping within an extracellular domain of Neurofascin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1106-1210 mapping within an extracellular domain of Neurofascin of human origin |
| Entrez Gene | 23114 |
|---|
| Application Notes | recommended for detection of Neurofascin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
