| Product Name | KLF12 Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 191-240 mapping within an internal region of KLF12 of human origin |
| Modification Notes | Krüppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and which coregulators they interact with. KLF12 (krüppel-like factor 12), also known as AP2REP or HSPC122, is a 402 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. One of several members of the Sp1 C2H2-type zinc-finger protein family, KLF12 binds to a regulatory element in the AP-2å gene promotor and, via this binding, functions as a strong repressor of AP-2å transcription. Two isoforms of KLF12 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of KLF12 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 191-240 mapping within an internal region of KLF12 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 191-240 mapping within an internal region of KLF12 of human origin |
| Entrez Gene | 11278 |
|---|
| Application Notes | recommended for detection of KLF12 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
