epitope mapping near the N-terminus of CCDC111 of human origin
Modification Notes
CCDC111 (coiled-coil domain containing 111) is a 560 amino acid protein encoded by a gene that maps to human chromosome 4q35.1. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of CCDC111 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other CCDC family members also reactive with additional species, including canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the N-terminus of CCDC111 of human origin
Tissue Specificity
epitope mapping near the N-terminus of CCDC111 of human origin
Western blot analysis of CCDC111 expression in non-transfected: (A) and human CCDC111 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of CCDC111 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other CCDC family members also reactive with additional species, including canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.