| Product Name | ENX-2 Antibody (H-97) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 164-260 mapping within an internal region of ENX-2 of human origin |
| Modification Notes | In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development (1,2). PcG proteins work in conjunction with the trithorax-group (trxG) proteins, which activate homeobox gene expression during embryonic develop-ment (3,4). ENX-1, a mammalian homolog of the Drosophila gene enhancer of zeste, is a PcG protein that is ubiquitously expressed during early embryogenesis and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development (3,5,6). In the adult, ENX-1 is restricted to specific sites, including spleen, testis and placenta (6). ENX-2 is another mammalian homolog of the Drosophila gene enhancer of zeste and contains one SET domain (7). The gene for human ENX-2 maps to chromosome 17q21(7). ENX-2 expression is ubiquitous in adult and fetal tissue, where it may aid in maintaining heterochromatin stability (7). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ENX-2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 164-260 mapping within an internal region of ENX-2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 164-260 mapping within an internal region of ENX-2 of human origin |
| Entrez Gene | 2145 |
|---|
| Application Notes | recommended for detection of ENX-2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
