Application
Western blot analysis of TDE2L expression in non-transfected: (A) and mouse TDE2L transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TDE2L expression in non-transfected: (A) and human TDE2L transfected: (B) 293T whole cell lysates.| Product Name | TDE2L Antibody (E-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of TDE2L of human origin |
| Modification Notes | TDE2L (tumor differentially expressed protein 2-like), also known as SERINC2 (serine incorporator 2), is a 456 amino acid multi-pass membrane protein that belongs to the TDE1 family. The gene that encodes TDE2L contains more than 25,000 bases and maps to human chromosome 1p35. With roughly 3,000 genes that span about 260 million base pairs, chromosome 1 makes up 8% of the human genome. There is also a large number of diseases associated with chromosome 1, notably, the rare aging disease Hutchinson-Gilford progeria, which is associated with the LMNA gene that encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TDE2L of human origin by WB, IP, IF and ELISA non cross-reactive with TDE1: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TDE2L of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TDE2L of human origin |
| Entrez Gene | 347735 |
|---|
Application
Western blot analysis of TDE2L expression in non-transfected: (A) and mouse TDE2L transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TDE2L expression in non-transfected: (A) and human TDE2L transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of TDE2L of human origin by WB, IP, IF and ELISA non cross-reactive with TDE1: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
