| Product Name | TXNDC15 Antibody (A-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within a C-terminal extracellular domain of TXNDC15 of human origin |
| Modification Notes | Thioredoxins comprise a family of small proteins that, by catalyzing the oxidation of disulfide bonds, participate in redox reactions throughout the cell. Proteins that contain thioredoxin domains do not necessarily convey the oxidative properties of thioredoxins, but generally function as disulfide isomerases that enzymatically rearrange disulfide bonds found in various proteins. TXNDC15 (thioredoxin domain containing 15), also known as UNQ335, is a 360 amino acid single-pass type I membrane protein that contains a thioredoxin domain. Existing as two alternatively spliced isoforms, TXNDC15 is encoded by a gene located on human chromosome 5q31.1. Human chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TXNDC15 isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other TXNDC family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a C-terminal extracellular domain of TXNDC15 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a C-terminal extracellular domain of TXNDC15 of human origin |
| Entrez Gene | 79770 |
|---|
| Application Notes | recommended for detection of TXNDC15 isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other TXNDC family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
