| Product Name | SUHW4 Antibody (Y-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of SUHW4 of human origin |
| Modification Notes | SUHW4 (suppressor of hairy wing homolog 4), also known as ZNF280D (zinc finger protein 280D) or ZNF634 (zinc finger protein 634), is a 979 amino acid nuclear protein that may function as a transcription factor. SUHW4 contains five C2H2-type zinc fingers and exists as five alternatively spliced isoforms. The gene that encodes SUHW4 contains 103,911 bases and maps to human chromosome 15q21.3. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease and Marfan syndrome are also associated with chromosome 15 through the HEXA gene and the FBN1 gene, respectively. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of SUHW4 of mouse and human origin by WB, IF and ELISA non cross-reactive with SUHW1 or SUHW3 also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of SUHW4 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of SUHW4 of human origin |
| Entrez Gene | 54816 |
|---|
| Application Notes | recommended for detection of SUHW4 of mouse and human origin by WB, IF and ELISA non cross-reactive with SUHW1 or SUHW3 also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
