Application
Western blot analysis of human recombinant neuroligin 3 fusion protein.| Product Name | neuroligin 3 Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 649-703 mapping within an extracellular domain of neuroligin 3 of human origin |
| Modification Notes | Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3 (1). Neuroligins are expressed in excitatory neuronal synaptic clefts (1,3,4). Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins (1,5). Neuroexin 1∫ binds to the EF-hand domain of Neuroligin 1 and requires calcium ion (2,6). Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses (7). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of neuroligin 3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 649-703 mapping within an extracellular domain of neuroligin 3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 649-703 mapping within an extracellular domain of neuroligin 3 of human origin |
| Entrez Gene | 54413 |
|---|
Application
Western blot analysis of human recombinant neuroligin 3 fusion protein.| Application Notes | recommended for detection of neuroligin 3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
