| Product Name | PHKG1 Antibody (N-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of PHKG1 of human origin |
| Modification Notes | PHKG1 (Phosphorylase kinase subunit ©1), is a subunit of phosphorylase kinase (PHK) that belongs to the Ser/Thr protein kinase family. PHK is a hexadecameric protein composed of four å chains, four ∫ chains, four © chains and four ∂ chains. The © chains are catalytic chains, the å and ∫ chains are regulatory chains and the ∂ chains are calmodulins. PHKG1 contains two calmodulin-binding domains and one protein kinase domain. As the catalytic chain of PHK, PHKG1 is responsible for catalyzing the phosphorylation and activation of glycogen phosphorylase and therefore it plays an important role in the glycogenolytic pathway. Mutations in the gene encoding PHKG1 can lead to PHK deficiency and result in glycogen storage disease type 9C (GSD9C), also known as autosomal liver glycogenosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PHKG1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with PHKG2 also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of PHKG1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of PHKG1 of human origin |
| Entrez Gene | 5260 |
|---|
| Application Notes | recommended for detection of PHKG1 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with PHKG2 also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
