| Product Name | melanopsin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 379-478 mapping at the C-terminus of melanopsin of human origin |
| Modification Notes | G protein coupled receptors (GPCRs) contain seven transmembrane helices and elicit G protein-mediated signaling cascades. The opsin family represents approximately 90 percent of all GPCRs and includes red, green, and blue-sensitive opsins, rhodopsin and melanopsin. Opsins consist of an apoprotein covalently linked to 11-cis-retinal that undergoes isomerization upon photon absorption. The photon-induced conformation change of opsin activates hundreds of G proteins. Mammalian melanopsin expression selectively occurs in the inner retina and not in the photoreceptor cells critical for vision. Melanopsin plays a nonessential role in the transduction of photic stimuli for light/dark entrainment. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of melanopsin of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 379-478 mapping at the C-terminus of melanopsin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 379-478 mapping at the C-terminus of melanopsin of human origin |
| Entrez Gene | 94233 |
|---|
| Application Notes | recommended for detection of melanopsin of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
