| Product Name | SLC35A3 Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 196-265 mapping within an internal region of SLC35A3 of human origin |
| Modification Notes | SLC35A3 (solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3) is a 325 amino acid multi-pass membrane protein that belongs to the SLC35A subfamily of the Nucleotide-Sugar Transporter (NST) family. Members of the NST family are transmembrane proteins that mediate the translocation of nucleotide-sugars from the cytosol to the interior lumen of the endoplasmic reticulum (ER) and the golgi apparatus via an antiport mechanism, exchanging nucleoside monophosphates for nucleotide-sugars. This activity of NSTs is important for providing an available source of nucleotide-sugars for glycoconjugate synthesis. Localizing to the golgi apparatus membrane, SLC35A3 functions as a monospecific UDP-GlcNAc transporter. In cattle, mutations in the gene encoding SLC35A3 can result in Complex Vertebral Malformation (CMV), a lethal disorder that is defined by fused and misshapen vertebrae near the cervico-thoracic junction. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SLC35A3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 196-265 mapping within an internal region of SLC35A3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 196-265 mapping within an internal region of SLC35A3 of human origin |
| Entrez Gene | 23443 |
|---|
| Application Notes | recommended for detection of SLC35A3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
