Application
Western blot analysis of Peripherin expression in non-transfected: (A) and mouse Peripherin transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Peripherin expression in PC-12 whole cell lysate.| Product Name | Peripherin Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 21-90 mapping near the N-terminus of Peripherin of human origin |
| Modification Notes | Peripherin is a type III intermediate filament protein (IFP) that is expressed in peripheral and some central nervous system (CNS) neurons. Peripherin activation is known to be induced by leukemia inhibitory factor (LIF). LIF activates Peripherin by inducing members of Stat transcription factor family to bind to a specific promoter element in the Peripherin gene. IL-6 is also known to induce Peripherin expression. Although it is not essential for neurite formation, Peripherin is necessary for cellular intermediate filament network formation. Peripherin, unlike most intermediate filament proteins, has been reported to be modified by tyrosine phosphorylation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Peripherin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 21-90 mapping near the N-terminus of Peripherin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 21-90 mapping near the N-terminus of Peripherin of human origin |
| Entrez Gene | 5630 |
|---|
Application
Western blot analysis of Peripherin expression in non-transfected: (A) and mouse Peripherin transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Peripherin expression in PC-12 whole cell lysate.| Application Notes | recommended for detection of Peripherin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
