Application
Western blot analysis of EF-CAB7 expression in non-transfected: (A) and human EF-CAB7 transfected: (B) 293T whole cell lysates.| Product Name | EF-CAB7 Antibody (N-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of EF-CAB7 of human origin |
| Modification Notes | Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of EF-CAB7 of human origin by WB, IP, IF and ELISA non cross-reactive with other EF-CAB family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of EF-CAB7 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of EF-CAB7 of human origin |
| Entrez Gene | 84455 |
|---|
Application
Western blot analysis of EF-CAB7 expression in non-transfected: (A) and human EF-CAB7 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of EF-CAB7 of human origin by WB, IP, IF and ELISA non cross-reactive with other EF-CAB family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
