Application
Western blot analysis of C16orf79 expression in U-87 MG (A) and LADMAC (B) whole cell lysates.| Product Name | C16orf79 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of C16orf79 of human origin |
| Modification Notes | C16orf79, also known as MGC21830, is a membrane protein that contains one BRICHOS domain. The gene that encodes C16orf79 maps to human chromosome 16p13.3. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of C16orf79 isoforms 1 and 2 of human origin by WB, IP, IF and ELISA non cross-reactive with other C16orf family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of C16orf79 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of C16orf79 of human origin |
| Entrez Gene | 283870 |
|---|
Application
Western blot analysis of C16orf79 expression in U-87 MG (A) and LADMAC (B) whole cell lysates.| Application Notes | recommended for detection of C16orf79 isoforms 1 and 2 of human origin by WB, IP, IF and ELISA non cross-reactive with other C16orf family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
